BBT401 Bioprocess Engineering Syllabus
AKTU B.Tech · 4th Semester · Unit-wise syllabus (effective 2023-24)
BBT401 Bioprocess Engineering (also written as KBT401) is a subject in Semester 4 of the AKTU B.Tech programme, prescribed by Dr. A.P.J. Abdul Kalam Technical University. It carries 4 credits with an L-T-P of 3-1-0. The syllabus is divided into 5 units: Sterilization, Ideal Reactor Operation. The complete unit-wise topic list, course outcomes and reference books are given below, taken from the official AKTU syllabus effective from 2023-24.
BBT401 Subject Details
| Subject Code | BBT401 / KBT401 |
|---|---|
| Subject Name | Bioprocess Engineering |
| University | Dr. A.P.J. Abdul Kalam Technical University (AKTU) |
| Course | B.Tech (Bachelor of Technology) |
| Year / Semester | 2nd Year · 4th Semester |
| Credits | 4 |
| L-T-P | 3-1-0 |
| Total Units | 5 |
| Scheme Effective From | 2023-24 |
| Last Verified | 2026-08-15 |
BBT401 Bioprocess Engineering Unit-Wise Syllabus
Official AKTU syllabus (effective 2023-24) — 5 units.
Unit 1
Media Preparation, Media design and optimization. Microbial growth patterns and kinetics in batch culture, Microbial growth parameters, Environmental conditions affect growth kinetics, Kinetics of thermal death of microorganisms, Heat Generation by microbial growth, Quantitative analysis of microbial growth by direct & indirect methods.
Unit 2: Sterilization
Sterilization: concept and methods. Type of Sterilizations, Batch heat sterilization of liquids, Estimation of sterilizer efficiency, Continuous heat sterilization of liquids, Sterilization of air: Methods &Mechanism, Design of depth filter and estimation of its efficiency. Stoichiometric calculations, Theoretical prediction of yield coefficients, Stoichiometry of growth and product formation, Maximum possible yield, Theoretical oxygen demand, Stoichiometry of single-cell protein synthesis.
Unit 3: Ideal Reactor Operation
Ideal Reactor Operation: Batch, Fed Batch & Continuous operation of mixed bioreactors, Microbial pellet formation, Kinetics and dynamics of pallet formation. Chemostate with immobilized cells, Chemostate with cell recycle, substrate utilization and product formation in bioreactor.
Unit 4
Role of diffusion in Bioprocessing, Convective mass transfer, Gas-liquid mass transfer, Oxygen uptake in cell cultures, Factor affecting cellular oxygen demand, Oxygen transfer in bioreactors, Measurement of volumetric oxygen transfer coefficient, Oxygen transfer in large bioreactor.
Unit 5
Bioreactor control mechanism, Physical, Chemical and Biological environment of bioreactor, Manual control system, Role of physical, chemical & biological sensors, Advanced control strategies viz. PID controllers, Fuzzy logic based controllers and artificial neural network based Controllers. Basic concepts of computer modeling and optimization in bioprocess applications.
BBT401 Course Outcomes
- At the end of course , the student will be able to
- CO 1 Comprehend the concept of media preparation, microbial growth and the associated K2
- parameters. K2
- K3
- CO 2 Demonstrate the concepts of sterilization necessary for proper bioreactor operation. K4
- K5, K6
- CO 3 Discuss the basics of ideal bioreactor operations and the kinetics of microbes. 3-1-0
- Proposed
- CO 4 Apply the concept of mass transfer, medium optimization and stoichiometric based Lecture
- calculations in bioprocessing.
- CO 5 Analyze the concept of bioreactor control mechanism and identify suitable control
- system.
BBT401 Reference Books
- Principles of Microbe and cell cultivation- S. John Pirt, Butterworth Publication.
- Bioprocess Engineering Principles – P. M. Doran, 5th ed.
- Hand Book Of Bioengineering- Skalak R & Shu Chien, 4th ed.
- Biochemical Engg. Bailly &Ollis, Academic Press
- Introduction to Chemical Engg. Series, MCH Int. Series.
- Biochemical & Biological Engg. Science, N. Blakebraugh, Academic Press
- "Principles of fermentation technology" by P F Stanbury and A Whitaker, Pergamon press.
Frequently Asked Questions about BBT401
What is the syllabus of BBT401 Bioprocess Engineering?
The AKTU BBT401 Bioprocess Engineering syllabus is divided into 5 units: Sterilization; Ideal Reactor Operation. The complete topic list for each unit is published on this page, taken from the official Dr. A.P.J. Abdul Kalam Technical University syllabus effective from 2023-24.
How many units are there in BBT401?
BBT401 Bioprocess Engineering has 5 units in the AKTU syllabus, with an L-T-P (Lecture-Tutorial-Practical) structure of 3-1-0 and 4 credits.
Is BBT401 the same subject as KBT401?
Yes. AKTU renumbered its B.Tech subject codes from the 2022-23 session onwards, so the same subject appears as BBT401 and KBT401 depending on the scheme year. The syllabus content is the same.
Which semester is BBT401 taught in?
BBT401 Bioprocess Engineering is taught in Semester 4 of the 2nd year of the AKTU B.Tech programme.
How many credits is BBT401 worth?
BBT401 Bioprocess Engineering carries 4 credits in the AKTU evaluation scheme, with an L-T-P of 3-1-0.
Where can I download BBT401 previous year question papers?
AKTU B.Tech previous year question papers for every semester are available to download free on Ryzenstudy, with no login or registration required.
Is this the official AKTU syllabus for BBT401?
Yes. Every topic on this page is taken from the official Dr. A.P.J. Abdul Kalam Technical University syllabus document (AKTU B.Tech 2nd Year Biotechnology Syllabus), effective from 2023-24. A direct link to the original AKTU PDF is provided at the top of this page. Last verified on 2026-08-15.
Related AKTU Syllabus
Source: Dr. A.P.J. Abdul Kalam Technical University official syllabus — AKTU B.Tech 2nd Year Biotechnology Syllabus, effective from 2023-24. Ryzenstudy is not affiliated with AKTU. Content last verified on 2026-08-15.