B.TechSemester 82024-25VirologyKOE087

Virology (KOE087) - AKTU Question Paper 2024-25

B.Tech · Semester 8 · Free PDF Download

This is the official AKTU Virology Previous Year Question Paper for B.Tech Semester 8, academic session 2024-25. Published by Dr. A.P.J. Abdul Kalam Technical University (AKTU/UPTU), Lucknow. Free PDF download — no login required.

Course:B.Tech

Semester:Semester 8

Session:2024-25

University:AKTU / UPTU

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Questions Asked in 2024-25

Virology (KOE087) — extracted question text · 100 marks · 3 Hours

Section AAttempt all questions in brief. 2 x 10 = 20

a
List two commonly used an tiretroviral drug classes
b
Name two viral diagnostic techni ques commonly used in clinical practice
c
Recall conventional vaccines? Mention two types
d
What do you mean by antiviral libraries
e
Exemplify one virus each from t he Herpesviridae and Poxviridae families
f
Which enzyme is responsible for converting viral RNA into DNA in retroviruses?
g
Outline two common shapes of viral capsids
h
Name the virus family responsible for dengue and state its gen ome type. 3 K1 i. Differentiate between cyt okines and interferon. 5 K2 j. What is a virion and how is it different from living organism? 1 K 1

Section BAttempt any three of the following: 10 x 3 = 30

a
Outline the basis of virus cla ssification systems and nomenc lature highlighting how genomic structure and replication strategies contribute to their taxonomy
b
Summarize the strategies used by retroviruses to integrate into the host genome and discuss how these strategies contribute to viral persistence and disease progression
c
Analyze the pathogenic mechanism of rabies viruses, highligh ting the host-virus interactions and immune responses involved in each
d
Describe the structure and re plication cycle of Influenza virus
e
Compare the naked and enveloped virus structures with two ex amples of each

Section CAttempt any one part of the following: 10 x 1 = 10

a
Differentiate between DNA v accine and subunit vaccine along with role of adjuvants in viral vaccine development
b
Interpret molecular biology of SARS-CoV and its public health impact
a
Explain the historical milest ones that led to the discovery and understanding of viruses
b
Demonstrate diagrammatically H IV structure, replication and pathogenesis of AIDS
a
Interpret, how viral infecti ons affects host macromolecules and cellular functions. Include examples of viruses that target specific host systems
b
Analyze the structural and pathogenic differences among +str and RNA viruses and Picornaviruses
a
Discuss the mechanism of oncoge nesis of any DNA virus
b
List the mechanism used by viruses to counter host antiviral defenses
a
Illustrate the principle and mechanism of siRNA and ribozyme s in modern viral control strategies
b
Explain the life-cycle of retr oviruses with special emphasis on reverse transcription

Question text is extracted from the official AKTU question paper PDF above. Check the original PDF for equations, diagrams and complete wording. Extracted: 2026-08-23.

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