B.PharmSemester 42023-24Medicinal Chemistry I – TheoryBP402T

Medicinal Chemistry I – Theory (BP402T) - AKTU Question Paper 2023-24

B.Pharm · Semester 4 · Free PDF Download

This is the official AKTU Medicinal Chemistry I – Theory Previous Year Question Paper for B.Pharm Semester 4, academic session 2023-24. Published by Dr. A.P.J. Abdul Kalam Technical University (AKTU/UPTU), Lucknow. Free PDF download — no login required.

Course:B.Pharm
Semester:Semester 4
Session:2023-24
University:AKTU / UPTU

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Questions Asked in 2023-24

Medicinal Chemistry I – Theory (BP402T) — extracted question text · 75 marks · 3 Hours

Section AAttempt all q u e s t i o n s i n b r i e f . 10 x 2 = 20
  • a
    Enlist the factors af fecting drug metabolism
  • b
    Discuss the importance of opt ical isomerism in relation to biological action
  • c
    Give the structure and uses of methyldopa
  • d
    Outline the biosynthesis of catecholamines
  • e
    Enlist cholinergic receptors and their distribution
  • f
    What is cholinesterase reactivator? Give example
  • g
    Give mechanism of action and s tructure of Chlorpromazine
  • h
    Outline the synthesis of phenytoin. i. What is dissociative ane sthesia? Give an example. j. State the use of narcotic antagonist. Give name and structur e of any two narcotic antagonists
Section BAttempt any two p a r t s o f t h e f o l l o w i n g : 2 x 10 = 20
  • a
    Compare Benzodiazepines and Barbiturates. Discuss in detail SAR of Benzodiazepines
  • b
    Discuss drug metabolism prin ciples and factors affecting drug metabolism
  • c
    Differentiate narcotic and non- narcotic analges ics with suit able examples. Outline in detail SAR of morphine analogues
Section CAttempt any five p a r t s o f t h e f o l l o w i n g : 7 x 5 = 35
  • a
    Outline the concept of bioisosterism in detail
  • b
    Discuss classification and SAR of sympathomimetic agents
  • c
    Classify adrenergic antagonist s. Discuss synthesis of tolazoline
  • d
    Give the MOA and synthesis of ( i) Carbachol (ii) Neostigmine
  • e
    Explain classification of Choli nolytic agents. Give synthesis of Ipratropium bromide
  • f
    What are antipsychotics? Outline classification of antipsych otics and discuss SAR of phenothiazines
  • g
    Classify anti-inflammatory age nts. Give synthesis of Mefenamic acid

Question text is extracted from the official AKTU question paper PDF above. Check the original PDF for equations, diagrams and complete wording. Extracted: 2026-08-23.

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