B.PharmSemester 42023-24Medicinal Chemistry I – TheoryBP402T

Medicinal Chemistry I – Theory (BP402T) - AKTU Question Paper 2023-24

B.Pharm · Semester 4 · Free PDF Download

This is the official AKTU Medicinal Chemistry I – Theory Previous Year Question Paper for B.Pharm Semester 4, academic session 2023-24. Published by Dr. A.P.J. Abdul Kalam Technical University (AKTU/UPTU), Lucknow. Free PDF download — no login required.

Course:B.Pharm
Semester:Semester 4
Session:2023-24
University:AKTU / UPTU

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Questions Asked in 2023-24

Medicinal Chemistry I – Theory (BP402T) — complete question paper · 75 marks · 3 Hours

Section AAttempt all q u e s t i o n s i n b r i e f . 10 x 2 = 20
  • a
    Enlist the factors af fecting drug metabolism
  • b
    Discuss the importance of opt ical isomerism in relation to biological action
  • c
    Give the structure and uses of methyldopa
  • d
    Outline the biosynthesis of catecholamines
  • e
    Enlist cholinergic receptors and their distribution
  • f
    What is cholinesterase reactivator? Give example
  • g
    Give mechanism of action and s tructure of Chlorpromazine
  • h
    Outline the synthesis of phenytoin. i. What is dissociative ane sthesia? Give an example. j. State the use of narcotic antagonist. Give name and structur e of any two narcotic antagonists
Section BAttempt any two p a r t s o f t h e f o l l o w i n g : 2 x 10 = 20
  • a
    Compare Benzodiazepines and Barbiturates. Discuss in detail SAR of Benzodiazepines
  • b
    Discuss drug metabolism prin ciples and factors affecting drug metabolism
  • c
    Differentiate narcotic and non- narcotic analges ics with suit able examples. Outline in detail SAR of morphine analogues
Section CAttempt any five p a r t s o f t h e f o l l o w i n g : 7 x 5 = 35
  • a
    Outline the concept of bioisosterism in detail
  • b
    Discuss classification and SAR of sympathomimetic agents
  • c
    Classify adrenergic antagonist s. Discuss synthesis of tolazoline
  • d
    Give the MOA and synthesis of ( i) Carbachol (ii) Neostigmine
  • e
    Explain classification of Choli nolytic agents. Give synthesis of Ipratropium bromide
  • f
    What are antipsychotics? Outline classification of antipsych otics and discuss SAR of phenothiazines
  • g
    Classify anti-inflammatory age nts. Give synthesis of Mefenamic acid

Question text is extracted from the official AKTU question paper PDF above. Hindi translations are omitted — every question is printed in English in the original paper. Last verified: 2026-08-23.

Repeated Questions — BP402T

Questions that appeared in more than one session, found by comparing 4 years of Medicinal Chemistry I – Theory papers (2021-22, 2022-23, 2023-24, 2024-25)

2x

Give the structure and uses of methyldopa

Appeared in: 2023-24 · 2024-25

2x

Outline the biosynthesis of catecholamines

Appeared in: 2023-24 · 2024-25

2x

Enlist cholinergic receptors and their distribution

Appeared in: 2021-22 · 2023-24

2x

What is cholinesterase reactivator? Give example

Appeared in: 2022-23 · 2023-24

2x

Give the MOA and synthesis of ( i) Carbachol (ii) Neostigmine

Appeared in: 2022-23 · 2023-24

Medicinal Chemistry I – Theory — Other Year Papers

AKTU Medicinal Chemistry I – Theory PYQs from other sessions