B.PharmSemester 42024-25Medicinal Chemistry I – TheoryBP402T

Medicinal Chemistry I – Theory (BP402T) - AKTU Question Paper 2024-25

B.Pharm · Semester 4 · Free PDF Download

This is the official AKTU Medicinal Chemistry I – Theory Previous Year Question Paper for B.Pharm Semester 4, academic session 2024-25. Published by Dr. A.P.J. Abdul Kalam Technical University (AKTU/UPTU), Lucknow. Free PDF download — no login required.

Course:B.Pharm

Semester:Semester 4

Session:2024-25

University:AKTU / UPTU

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Questions Asked in 2024-25

Medicinal Chemistry I – Theory (BP402T) — complete question paper · 75 marks · 3 Hours

Section AAttempt all questions in brief. 10 x 2 = 20

a
Define bioisosterism and give one example
b
What are Phase I reactions in drug metabolism?
c
Write the structure and use of phenylephrine
d
Give SAR of beta-blockers in brief
e
Differentiate between reversible and irreversible cholineste rase inhibitors
f
Write the synthesis and use of Neostigmine
g
What are barbiturates? Write any two examples
h
Write the mechanism of action of phenytoin. i. Mention the SAR of morphine analogues. j. Write the structure and therapeutic use of ibuprofen

Section BAttempt any two parts of the following: 2 x 10 = 20

a
Describe in detail the physicochemical properties in relatio n to biological activity
b
Classify adrenergic agonists in detail . Explain the SAR of sympathomimetic agents with examples
c
Discuss the synthesis, mechan ism, and SAR of cholinergic blocking agents

Section CAttempt any five parts of the following: 7 x 5 = 35

a
Discuss the factors affecti ng drug metabolism including stereochemical aspects
b
Explain the biosynthesis and catabolism of catecholamines
c
Describe the SAR of benzodiazepines and write the structure of diazepam
d
Classify antipsychotic drugs . Explain SAR of phenothiazines
e
Write a short note on mechanis m of action and synthesis of carbamazepine
f
Describe the classification and uses of general anesthetics
g
Discuss the structure, uses, a nd SAR of NSAIDs with special reference to ibuprofen and mefenamic acid

Question text is extracted from the official AKTU question paper PDF above. Hindi translations are omitted — every question is printed in English in the original paper. Last verified: 2026-08-23.

Repeated Questions — BP402T

Questions that appeared in more than one session, found by comparing 4 years of Medicinal Chemistry I – Theory papers (2021-22, 2022-23, 2023-24, 2024-25)

Define bioisosterism and give one example

Appeared in: 2022-23 · 2024-25

Write the structure and use of phenylephrine

Appeared in: 2023-24 · 2024-25

Describe in detail the physicochemical properties in relatio n to biological activity

Appeared in: 2022-23 · 2024-25

Explain the biosynthesis and catabolism of catecholamines

Appeared in: 2023-24 · 2024-25

Medicinal Chemistry I – Theory — Other Year Papers

AKTU Medicinal Chemistry I – Theory PYQs from other sessions

Medicinal Chemistry I – Theory2023-24

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