Medicinal Chemistry I – Theory (BP402T) - AKTU Question Paper 2024-25
B.Pharm · Semester 4 · Free PDF Download
This is the official AKTU Medicinal Chemistry I – Theory Previous Year Question Paper for B.Pharm Semester 4, academic session 2024-25. Published by Dr. A.P.J. Abdul Kalam Technical University (AKTU/UPTU), Lucknow. Free PDF download — no login required.
Course:B.Pharm
Semester:Semester 4
Session:2024-25
University:AKTU / UPTU
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Questions Asked in 2024-25
Medicinal Chemistry I – Theory (BP402T) — extracted question text · 75 marks · 3 Hours
Section AAttempt all questions in brief. 10 x 2 = 20
- aDefine bioisosterism and give one example
- bWhat are Phase I reactions in drug metabolism?
- cWrite the structure and use of phenylephrine
- dGive SAR of beta-blockers in brief
- eDifferentiate between reversible and irreversible cholineste rase inhibitors
- fWrite the synthesis and use of Neostigmine
- gWhat are barbiturates? Write any two examples
- hWrite the mechanism of action of phenytoin. i. Mention the SAR of morphine analogues. j. Write the structure and therapeutic use of ibuprofen
Section BAttempt any two parts of the following: 2 x 10 = 20
- aDescribe in detail the physicochemical properties in relatio n to biological activity
- bClassify adrenergic agonists in detail . Explain the SAR of sympathomimetic agents with examples
- cDiscuss the synthesis, mechan ism, and SAR of cholinergic blocking agents
Section CAttempt any five parts of the following: 7 x 5 = 35
- aDiscuss the factors affecti ng drug metabolism including stereochemical aspects
- bExplain the biosynthesis and catabolism of catecholamines
- cDescribe the SAR of benzodiazepines and write the structure of diazepam
- dClassify antipsychotic drugs . Explain SAR of phenothiazines
- eWrite a short note on mechanis m of action and synthesis of carbamazepine
- fDescribe the classification and uses of general anesthetics
- gDiscuss the structure, uses, a nd SAR of NSAIDs with special reference to ibuprofen and mefenamic acid
Question text is extracted from the official AKTU question paper PDF above. Check the original PDF for equations, diagrams and complete wording. Extracted: 2026-08-23.
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