B.PharmSemester 82024-25Computer Aided Drug DesignBP807ET
View PDFDownload

Computer Aided Drug Design (BP807ET) - AKTU Question Paper 2024-25

B.Pharm · Semester 8 · Free PDF Download

This is the official AKTU Computer Aided Drug Design Previous Year Question Paper for B.Pharm Semester 8, academic session 2024-25. Published by Dr. A.P.J. Abdul Kalam Technical University (AKTU/UPTU), Lucknow. Free PDF download — no login required.

Course:B.Pharm
Semester:Semester 8
Session:2024-25
University:AKTU / UPTU

Rate this paper

Questions Asked in 2024-25

Computer Aided Drug Design (BP807ET) — complete question paper · 75 marks · 3 Hours

Section BAttempt any two parts of the following: 2 x 10 = 20
  • a
    Elaborate analogue based drug design giving emphasis on obje ctives and categories of analogue designing
  • b
    Discuss Hammet’s substituent c onstant, Taft’s steric constant and Hansch analysis and its role in predicting biological activity
  • c
    Define pharmacophore. Discuss concept of pharmacophore mappi ng and pharmacophore-based screen
Section CAttempt any five parts of the following: 7 x 5 = 35
  • a
    What is molecular docking? How does flexible docking differ from rigid docking in molecular docking studies?
  • b
    How does chemoinformatics contribute to drug discovery? Expl ain steps involved in chemical data curation
  • c
    Discuss various energy minimization techniques used in molec ular modelling study
  • d
    How do similarity-based methods in virtual screening help id entify potential drug candidates? Discuss key techniques used to measure molecular similarity
  • e
    Define and classify bio-isosters. Explain bio-isosterism app roach with examples
  • f
    Discuss the role of molecul ar mechanics in drug design
  • g
    Write an elaborative note on De novo drug design with exampl e
  • a
    Define log P and explain how it relates to the partition coefficient
  • b
    How does QSAR differ from SAR, and what advantages does it o ffer?
  • c
    What is a biochemical database?
  • d
    Compare random screening and non-random screening approaches
  • e
    What is conformatio nal analysis, and why is it important in SAR of a drug molecule?
  • f
    What is bioinformatics, and h ow is it used in modern biological research?
  • g
    Enlist two ADM E databases
  • h
    Name any two physicochemical properties commonly used to ass ess drug-likeness i. Explain COMFA and COMSIA. j. What is lead optimiza tion in drug discovery?

Question text is extracted from the official AKTU question paper PDF above. Hindi translations are omitted — every question is printed in English in the original paper. Last verified: 2026-08-23.

Computer Aided Drug Design — Other Year Papers

AKTU Computer Aided Drug Design PYQs from other sessions

Computer Aided Drug Design2022-23

More B.Pharm Semester 8 (2024-25) Papers

Other subjects from same semester and session

Biostatistics And Research Methodology2024-25Pharma Marketing Management2024-25Experimental Pharmacology2024-25Social And Preventive Pharmacy2024-25Pharmaceutical Product Development2024-25Cell And Molecular Biology2024-25Dietary Supplements And Nutraceuticals2024-25
View all B.Pharm Semester 8 2024-25 papers →